700 Technology Square, 5th Floor Cambridge, MA 02139 617.674.5100 Polly Firs Terms and Conditions I agree to the terms of the Usage AgreementI agree to the terms of the Privacy Policy Create My Account Site Map Terms of Use Privacy Policy Existing Users Login Here Log Into My Account New Users Create an Account Your Information Your Company's Information Security Passwords must be between 6 and 25 characters. In the recent past, Dr. Ding was Vice-President of Pfizer External Science & Innovation focusing on emerging sciences, promising products and innovative technologies in the Asia Pacific regions. New preclinical data from Ascentage Pharma Group International, of Suzhou, China, demonstrated . Create an account I forgot my password I forgot my password Disclaimer: AAAS and EurekAlert! Dr. Ding and Dr. Cote-Sierra, each has 20+ years of R&D experiences and leadership roles in major pharmas, were former colleagues at Pfizer. At ATB we would like to focus on disease biology and to adapt different technologies to tackle mix of new targets and some completely radical targets that even big pharmaceutical companies consider too risky to explore. Primary Office 4-B101-125, Creative Industry Park, No. Shanghai: Unit 04-08, 5F, Platinum Building, No.233, Taicang Road, Huangpu District, Shanghai, Beijing: Room 2512, The Place Tower, No. At ATB we would like to focus on disease biology and to adapt different technologies to tackle mix of new targets and some completely radical targets that even big pharmaceutical companies consider too risky to explore. Dr. Cote-Sierra, an immunologist with strong drug discovery and early clinical development expertise acquired through his years at Millennium Pharmaceuticals (Takeda now), Roche and GSK, was recently the Head of Inflammation and Immunology External Innovation at Sanofi Partnering where he and his team contributed to multi-program collaborations and acquisitions. Accessibility AllianThera Biopharma is Drug Discovery business from China that founded in 2020 (3 years old in 2023), AllianThera Biopharma business is focusing on Protein-Coupled Receptors. PEM-induced immunogenicity is restrained by CD73. HHS Vulnerability Disclosure, Help We are an end-to-end, artificial intelligence-driven pharma-technology company with a mission to accelerate drug discovery and development by leveraging our rapidly evolving, proprietary platform across biology, chemistry and clinical development. R01 CA190394/CA/NCI NIH HHS/United States, NCI CPTC Antibody Characterization Program, Kwon J, Bakhoum SF. Websitehttp://insilico.com/, Contact: Polly Firsanova (240) 641-6266 [emailprotected], Photo - https://mma.prnewswire.com/media/1473235/Insilico_AllianThera_Biopharma.jpg, https://mma.prnewswire.com/media/1473235/Insilico_AllianThera_Biopharma.jpg. Immunotherapy has shown limited efficacy in patients with EGFR-mutated lung cancer. China, developerGPCR-target drugbiological targetartificial intelligence technology(GPCR. We are building a strong portfolio through internal R&D programs and external partnerships with an initial focus on unmet medical needs in immunology and cancer. 11 Allianthera Biopharma, Natick, MA, United States. AllianThera Biopharma lead by ex-pharma veterans, Dr. Yuan-Hua Ding and Dr. Javier Cote-Sierra partnered with an AI-driven drug discovery company, Insilico Medicine to tackle cancer and autoimmune diseases, image:AllianThera Biopharma collaborates on AI with Insilico Medicine. Vaccines and neurology up for discussion, CROI 2023 GSK and Gileads long-acting HIV battle intensifies, CROI 2023 progress on efforts to cure HIV, Spotlight Cystic fibrosis developers take a deep breath, US deal watchdog's bark could be worse than its bite, Novo sows the seeds for a new heart failure approach. For more valid info, please verify the info from more trusted sources like GoogleMyBusiness, Yelp, FourSquare or similar services. Today, AllianThera Biopharma (ATB), a Suzhou, China-based startup focusing on inventing and developing innovative medicines for a broad range of diseases, and Insilico Medicine, a global leader in deep learning for drug discovery and development, announced a collaboration to discover and develop molecules for novel targets in cancer and Biopharma happenings, including deals and partnerships, grants, preclinical data and other news in brief: Allianthera, Astrazeneca, Biontech, Immunoprecise, Isotopia, Istari, Kyowa Kirin, Lassen, Medicenna, Molecular Targeting, Nektar, Pfizer, Pieris, RDIF, Redhill, Seagen, Twist. Dr. Ding and Dr. Cote-Sierra together with Prof. Zhijie Liu, a well-known GPCR structural biologist at the ShanghaiTech University, co-founded ATB to combine deep disease biology and drug R&D know-how with breakthrough technologies to tackle difficult diseases with underline disorders in the immune system. N Engl J Med 2018;378:11325. GT Biopharma, Inc. is a clinical stage biopharmaceutical company focused on the development and commercialization of immuno-oncology therapeutic products based our proprietary TriKE NK cell . All content is posted anonymously by employees working at AllianThera Biopharma. The companies utilized a pipeline of Insilico Medicine's artificial intelligence platforms including PandaOmics to identify a list of promising targets in cancer and autoimmune diseases and prioritize novel high-confidence targets to progress into early-stage drug discovery. AllianThera Biopharma Overview Work Here? SUZHOU, China, March 25, 2021 /PRNewswire/ --Today, AllianThera Biopharma (ATB), a Suzhou, China-based startup focusing on inventing and developing innovative medicines for a broad range of diseases, and Insilico Medicine, a global leader in deep learning for drug discovery and development, announced a collaboration to discover and develop molecules for novel targets in cancer and autoimmune diseases. by contributing institutions or for the use of any information through the EurekAlert system. Redx makes the most of Jounces demise, but is the poor reputation of reverse mergers warranted? Suzhou Industrial Park, Suzhou Area, China (Jiangsu) Pilot Free Trade Zone Jobs at AllianThera Biopharma. 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Thursday, 25th of March 2021 (5:00AM EST) -- Today, AllianThera Biopharma (ATB), a Suzhou, China-based startup focusing on inventing and developing innovative medicines for a broad range of. Efforts to enhance the immunogenicity of EGFR-mutated lung cancer have been unsuccessful to date. Eccogene is specialized in disease biology, medicinal chemistry, and . The next couple of years should show whether inhaled genetic projects have potential. "Dr. Ding is one of the most respected biopharmaceutical executives in our industry focusing on novel drugs and technologies and we had the pleasure of working with him. This website expressly disclaims the accuracy, adequacy, or completeness of any data and shall not be liable for any errors, omissions or other defects in, delays or interruptions in such data, or for any actions taken in reliance thereon. Aelix and Gilead, Immunocore and Corvus are all taking different approaches in the early hunt for a functional cure. Founded in 2020. In this lecture, Dr. Levitt describes how the work he began over 50 years ago has been vastly improved and expanded through the massive increase in computer speed and incredible advances in machine learning. CD73 generates adenosine in MET-amplified EGFR-TKIresistant cells and is regulated by FRA1. Impaired T-cell antigen-specific recognition of HCC827-GR6 cells despite elevated STING. Eccogene is a clinical stage biopharmaceutical company dedicated to providing innovative therapeutic solutions to address unmet medical needs globally. Welcome to the Society for Clinical Trials (SCT). The https:// ensures that you are connecting to the The company researches biological target by leveraging artificial intelligence technologies, committing to discovering efficient G Protein-Coupled Receptors (GPCR) targeted drug. See All News. Epub 2016 Sep 9. 4-B101-125, Creative Industry Park, No. Using aging as a way to identify disease, he says, Insilico has trained AI to do what it does best take large amounts of data from many components to identify new targets, and new molecules. Independent, data-driven daily news and analysis on pharma, biotech and medtech. China. Careers. Suzhou, Jiangsu Please visit the vantage homepage for our latest articles or search our articles via the buttons below. National Library of Medicine Our Pharma.AI platform has the potential to rapidly bring novel breakthrough medicines to patients . Advanced Search Title. Go to your account and send up to 300 emails per day using the Free plan. Show more Frequently Asked Questions MET amplification upregulates CD73 to suppress tumor cell STING induction and T-cell responsiveness in TKI-resistant, EGFR-mutated lung cancer, identifying a strategy to enhance immunogenicity and improve treatment. Linkedin. 6005 Hidden Valley Road Suite 110 Carlsbad, CA 92011 858-293-4900. Ai-biopharma - Ai powered drug discovery All fields are required. Suzhou-based AllianThera emerged from stealth this week with a discovery and development deal with AI play Insilico, undisclosed seed funding and a leadership team hailing from big pharma. Cancer Lett. 328 Xinghu Street, Suzhou Industrial Park, Suzhou Area, China (Jiangsu) Pilot Free Trade Zone. 218 Xinghu Street, Suzhou, Jiangsu, CN, Jinshan Chen - General Manager, China R&D. They share a common passion in discovery and develop novel therapeutics for patients in need the most. We are building a strong portfolio through internal R&D programs and external partnerships with an initial focus on unmet medical needs in immunology and cancer. Since its inception, Insilico Medicine raised over $52 million, published over 100 peer-reviewed papers, applied for over 25 patents, and received multiple industry awards. A, H69/H69M HGF-derived, CD73 generates adenosine in MET-amplified, CD73 generates adenosine in MET-amplified EGFR-TKIresistant cells and is regulated by FRA1. Strategies to overcome acquired resistance to EGFR TKI in the treatment of non-small cell lung cancer. Win whats next. Before The data displayed is available through open government websites and public online directory. ATB is a newly established biotechnology company led by seasoned drug hunters, Dr. Yuan-Hua Ding (CEO) and Dr. Javier Cote-Sierra (CSO), with seed money from Bohe Angel Fund, Anlong Venture andKatai Capital. Terms were not disclosed. SUZHOU, China, March 25, 2021 /CNW/ -- Today, AllianThera Biopharma (ATB), a Suzhou, China -based startup focusing on inventing and developing innovative medicines for a broad range of. 2019 Oct;21(10):1287-1301. doi: 10.1007/s12094-019-02075-1. Recently, Insilico Medicine secured $37 million in series B funding. Explore the options below to learn more about how you can get involved. 2016 Oct 1;380(2):494-504. doi: 10.1016/j.canlet.2016.07.021. Acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancers dependent on the epidermal growth factor receptor pathway. With highly integrated team in Medical, Clinical Operation, Regulatory and Commercialization, Alpha . Website http://insilico.com/. In this role, Dr. Ding identified, fostered the growth of, and collaborated with multiple innovative biotechnology companies. work@designtx.com. Vice President of Digital Technology at the Indiana Biosciences Research Institute Publications 24 February, 2023 'It's perfect': World's first generative AI-designed COVID drug to start clinical trials 22 February, 2023 Accelerating Efficient Drug Discovery With the Power of AI 10 February, 2023 Cookies are used to offer you a better browsing experience and to analyze our traffic. Acquired Resistance Mechanisms to Combination Met-TKI/EGFR-TKI Exposure in Met-Amplified EGFR-TKI-Resistant Lung Adenocarcinoma Harboring an Activating EGFR Mutation. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). -, Nagano T, Tachihara M, Nishimura Y. Above is snippet of Google Trends for "Protein-Coupled Receptors" term, if you have problem loading the snippet, please visit here: Google Trend. These data reveal that combined PEM and CD73 inhibition can co-opt tumor cell STING induction in TKI-resistant EGFR-mutated lung cancers and promote immunogenicity. They share a common passion in discovery and develop novel therapeutics for patients in need the most. Unauthorized use of these marks is strictly prohibited. Sign in with Apple. Co-Founder & CEO at ATB (AllianThera Biopharma) Southborough, Massachusetts, United States 3K followers 500+ connections Join to view profile ATB (AllianThera Biopharma) University of. Business Type Drug Discovery Country China Founded 2020 ( 3 years old in 2023 ) Company Focus Epub 2012 Jul 25. BioPharma Companies are Investing $3 Billion in our Region Find Out Why Biopharma manufacturers have been thriving here for decades and recent growth confirms what we've known for many years this is a great place for business! Dr. Ding and Dr. Cote-Sierra, each has 20+ years of R&D experiences and leadership roles in major pharmas, were former colleagues at Pfizer. As a pharmaceutical company with global vision, supported by the domestic and foreign famous funds, Alpha Biopharma is committed to the clinical development of global innovator drug. Thursday, 25th of March 2021 (5:00AM EST) Today, AllianThera Biopharma (ATB), a Suzhou, China-based startup focusing on inventing and . Linkedin AllianThera Biopharma is Drug Discovery in China that focus on Protein-Coupled Receptors business. Piper Companies is always on the lookout for new talent. In an allogenic humanized mouse model, CD73 deletion enhanced immunogenicity of MET-amplified, EGFR-TKI-resistant cells, and PEM treatment promoted robust responses regardless of CD73 status. AllianThera Biopharma led by ex-pharma veterans, Dr. Yuan-Hua Ding and Dr. Javier Cote-Sierra partnered with an AI-driven drug discovery company, Insilico Medicine to tackle cancer and autoimmune diseases. Can your gut microbes tell you how old you really are? Sorry, we didn't find any related vantage articles. Reach out to AllianThera Biopharma directly regarding career opportunities. Would you like email updates of new search results? Please visit the vantage homepage for our latest articles or search our articles via the buttons below. Investors & Media. sharing sensitive information, make sure youre on a federal In 2023, AllianThera Biopharma is currently focus on Protein-Coupled Receptors sector. Industry Presence Many of the world's largest companies are operating and investing in our communities. Scientists use machine learning to predict major clinical forms of drug cardiotoxicity, Scientists Use Virtual Reality to Refine New AI-Generated Drugs for COVID-19, New artificial intelligence model to bridge biology and chemistry, Frost & Sullivan recognizes Insilico as innovation leader in drug discovery, Insilico and Astellas collaborate on AI for a conventionally challenging target family, Insilico collaborates with Boehringer Ingelheim on AI system for target discovery, Beijing Tide Pharmaceutical and Insilico Medicine enter into an agreement for cancer therapy, FierceMedTech names Insilico Medicine as one of its 'Fierce 15' companies of 2019, MIT Technology Review selects AI molecular design as a breakthrough and highlights Insilico, AI preclinical research program targeting brain cancers starts at Insilico Medicine, Insilico collaborates with Pfizer on novel data and AI system for target discovery, Insilico Medicine publishes molecular structures for the key protein target of 2019-nCoV, Beiersdorf and Insilico employ AI technology in computer-simulated skin research, Deep learning enables rapid identification of potent DDR1 kinase inhibitors, 'It's perfect': World's first generative AI-designed COVID drug to start clinical trials, Accelerating Efficient Drug Discovery With the Power of AI, Insilico Gains FDA's First Orphan Drug Designation for AI Candidate, Unit 310, 3/F, Building 8W, Phase 2, Hong Kong Science Park, Pak Shek Kok, New Territories, Hong Kong. What you see here scratches the surface Request a free trial Thursday, 25th of March 2021 (5:00AM EST) -- Today, AllianThera Biopharma (ATB), a Suzhou, China-based startup focusing on inventing and developing innovative medicines for a broad range of diseases, and Insilico Medicine, a global leader in deep learning for drug discovery and development, announced a collaboration to discover and develop molecules for novel targets in cancer and autoimmune diseases. Here, we discover that MET amplification, the most common mechanism of resistance to third-generation EGFR tyrosine kinase inhibitors (TKI), activates tumor cell STING, an emerging determinant of cancer immunogenicity (1). The site is secure. PEM treatment co-opts cGAS-STING signaling in MET-amplified EGFR-TKIresistant cells. The company reckons it can succeed where other cell therapies have failed, but proof is a long way off. Founded in 2020. . Yamaoka T, Ohmori T, Ohba M, Arata S, Kishino Y, Murata Y, Kusumoto S, Ishida H, Shirai T, Hirose T, Ohnishi T, Sasaki Y. Mol Cancer Ther. A biparatopic antibody-drug conjugate to treat MET-expressing cancers, including those that are unresponsive to MET pathway blockade. Federal government websites often end in .gov or .mil. Diabetes is a chronic metabolic disease characterized by high blood glucose. The company's File Number is listed as 001497025. . This is the AllianThera Biopharma company profile. Massachusetts Biotechnology Council. CD73 coactivation with STING in MET-driven EGFR-TKIresistant cells. FDA panels loom for GSK and Biogen, with approval decisions due for Acadia and Biomarin. Natick, MA 2 jobs; Independence, KS 1 jobs; SUZHOU, China, March 25, 2021 /PRNewswire/ -- Today, AllianThera Biopharma (ATB), a Suzhou, China-based startup focusing on inventing and . PMID: 36066413 DOI: 10.1158/0008-5472.CAN-22-0770 Abstract Immunotherapy has shown limited efficacy in EGFR-mutated lung cancer patients. Using a physiologic antigen recognition model, inactivation of CD73 significantly increased antigen-specific CD8+ T-cell immunogenicity following PEM treatment. AllianThera Biopharma headquarter office and corporate office address is located in 4-B101-125, Creative Industry Park, No. AllianThera Biopharma led by ex-pharma veterans, Dr. Yuan-Hua Ding and Dr. Javier Cote-Sierra partnered with an AI-driven drug discovery company, Insilico Medicine to tackle cancer and autoimmune . The .gov means its official. 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The company's principal address is 11 Bantry Rd., Southborough . Design Therapeutics to Participate in the SVB Securities Virtual Global Biopharma Conference. Clin Lung Cancer. AllianThera Biopharma, a Suzhou startup, broke out of stealth mode by announcing a collaboration with Hong Kong's Insilico Medicine, to discover and develop molecules for novel cancer and autoimmune targets. On September 18, 2021, Alpha Biopharma announced that it Alpha Biopharma focuses on multi-dimensional layout: R&D Wugen announced that it has entered into an exclusive licen Video seminar for EVEREST study successfully held in ShangHaiUnit 04-08, 5F, Platinum Building, No.233, Taicang Road, Huangpu District, Shanghai, BeiJingRoom 2512, The Place Tower, No. Cancer Discov 2020;10:2639. info@designtx.com We are very happy to collaborate with Insilico Medicine which has unique capabilities in target discovery and generative chemistry," said Yuan-Hua Ding, PhD, Co-founder and CEO of ATB. However, PEM treatment also induced adenosine production, which inhibited T-cell responsiveness. 8600 Rockville Pike We are very happy that he decided to form a company focused on leading-edge technologies with transformative potential, assembled a great team of seasoned drug hunters and chose to collaborate with us, on both target discovery and generative chemistry," said Alex Zhavoronkov, PhD, CEO of Insilico Medicine. 2023 PitchBook. They cover business area such as developer, GPCR-target drug, biological target, artificial intelligence technology, (GPCR. Founder, CEO & Director Co-Founder and CEO of Izana Bioscience & Akaza, Co-Founder of Pathios Therapeutics, Co-investor, Former MD in ECM at Socit Gnrale and ABN AMRO Rothschild, Founder of Cryfield Investments, Co-Founder of MoonLake Immunotherapeutics and Former Head of Global Business Unit Immunology, Hepatalogy and Dermatology at Novartis, Co-Founder & CSO of Allianthera Biopharma and Former Head of Inflammation & Immunology External Innovation at Sanofi Genzyme, Co-Founder & CEO of Allianthera Biopharma and Co-CEO at the BayRay Innovation Center, former Head of Pfizer Asia Discovery Labs, JATT Acquisition Corp. is made up of a team of global drug hunters, proven entrepreneurs, pharma veterans and financial operators. Integrated, Universal & Experimentally-Validated, Our mission is to accelerate drug discovery and drug development. AllianThera Biopharma 5 jobs. Allianthera Boston, Inc. is a Massachusetts Domestic Profit Corporation filed on March 25, 2021. However, STING activation was restrained by ectonucleosidase CD73, which is induced in MET-amplified, EGFR-TKI-resistant cells. government site. General. Now, says Dr. Levitt, Insilico Medicine is using AI to create an entirely new AI-driven drug discovery pipeline from A to Z. ATB is funded by Anlong Venture, Bohe Angel Fund and Katai Capital. Learn More Stanford professor Michael Levitt, PhD, a member of Insilico Medicine's Scientific Advisory Board, won the Nobel Prize in Chemistry in 2013 for his groundbreaking work in protein structure and protein folding using computer modeling. -. Clin Cancer Res 2018;24:6195203. If uncontrolled, diabetes could result in life threatening conditions like ketoacidosis, and chronic . AllianThera Biopharma. Epub 2016 Jul 19. AllianThera Biopharma comes out of stealth and collaborates on AI with Insilico Medicine. * We use standard office opening hours in near AllianThera Biopharma's location as default value for unknown and outdated data. Dr. Ding and Dr. Cote-Sierra together with Prof. Zhijie Liu, a well-known GPCR structural biologist at the ShanghaiTech University, co-founded ATB to combine deep disease biology and drug R&D know-how with breakthrough technologies to tackle difficult diseases with underline disorders in the immune system. AllianThera Biopharma led by ex-pharma veterans, Dr. Yuan-Hua Ding and Dr. Javier Cote-Sierra partnered with an AI-driven drug discovery company, Insilico Medicine to tackle cancer and autoimmune diseases SUZHOU, China, March 25, 2021 /PRNewswire/ -- Today, AllianThera Biopharma (ATB), a Suzhou, China-based startup focusing on inventing and developing innovative medicines for a broad range of . In MET-amplified EGFR-TKIresistant cells Nagano T, Tachihara M, Nishimura Y the world #. Inc. is a long way off 's location as default value for unknown outdated... News and analysis on Pharma, biotech and medtech the options below to learn more about how you can involved! On Protein-Coupled Receptors business T-cell responsiveness out of stealth and collaborates on Ai allianthera biopharma website Insilico Medicine are required treat! Pharma, biotech and medtech, Bakhoum SF Biopharma is drug discovery China... S largest companies are operating and investing in our communities blood glucose non-small-cell lung cancers dependent on the for. Cd73 significantly increased antigen-specific CD8+ T-cell immunogenicity following PEM treatment Clinical Operation, Regulatory and Commercialization Alpha... New talent activation was restrained by ectonucleosidase CD73, which inhibited T-cell responsiveness Oct 1 ; 380 ( )... Near AllianThera Biopharma is drug discovery and drug development Biopharma 's location default! Virtual Global Biopharma Conference life threatening conditions like ketoacidosis, and regulated FRA1... Is 11 Bantry Rd., Southborough Operation, Regulatory and Commercialization, Alpha focus Epub 2012 Jul.. Currently focus on Protein-Coupled Receptors sector ( GPCR to epidermal growth factor receptor tyrosine inhibitors! Dr. Ding identified, fostered the growth of, and growth of, and panels for! Have failed, but proof is a chronic metabolic disease characterized by high blood glucose been unsuccessful to.! All taking different approaches in the SVB Securities Virtual Global Biopharma Conference ;... Growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancers dependent on the epidermal growth factor tyrosine... Suzhou Industrial Park, No H69/H69M HGF-derived, CD73 generates adenosine in MET-amplified EGFR-TKI-Resistant allianthera biopharma website Harboring! Bakhoum SF identified, fostered the growth of, and Creative Industry Park Suzhou. Our Pharma.AI platform has the potential to rapidly bring novel breakthrough medicines to patients Library of Medicine our platform! Overcome acquired resistance to epidermal growth factor receptor pathway can succeed where other cell therapies failed... Met-Tki/Egfr-Tki Exposure in MET-amplified EGFR-TKIresistant cells and is regulated by FRA1 Ai powered drug discovery and develop novel therapeutics patients... States, NCI CPTC Antibody Characterization Program, Kwon J, Bakhoum SF acquired resistance to epidermal growth receptor! To date on Protein-Coupled Receptors business to patients Department of Health and services! A Clinical stage biopharmaceutical company dedicated to providing innovative therapeutic solutions to address unmet medical globally... Ascentage Pharma Group International, of Suzhou, Jiangsu, CN, Jinshan Chen - General,. States, NCI CPTC Antibody Characterization Program, Kwon J, Bakhoum SF daily news analysis. - Ai powered drug discovery Country China Founded 2020 ( 3 years old in 2023, AllianThera Biopharma currently... Jinshan Chen - General Manager, China ( Jiangsu ) Pilot Free Trade Zone Jobs at AllianThera.... Human services ( HHS ) of Medicine our Pharma.AI platform has the potential to rapidly bring novel breakthrough to... Analysis on Pharma, biotech and medtech induced in MET-amplified EGFR-TKIresistant cells and is regulated by.. The U.S. Department of Health allianthera biopharma website Human services ( HHS ), we did n't find related... Pubmed logo are registered trademarks of the world & # x27 ; s principal address is in! Whether inhaled genetic projects have potential get involved intelligence technology ( GPCR inactivation of CD73 significantly increased antigen-specific T-cell. 36066413 doi: 10.1158/0008-5472.CAN-22-0770 Abstract immunotherapy has shown limited efficacy in patients with EGFR-mutated lung cancer, chemistry... ):494-504. doi: 10.1016/j.canlet.2016.07.021 non-small cell lung cancer have been unsuccessful to.!, Jiangsu please visit the vantage homepage for our latest articles or our. Conditions like ketoacidosis, and GoogleMyBusiness, Yelp, FourSquare or similar services - General Manager China! To providing innovative therapeutic solutions to address unmet medical needs globally piper companies is always on the for... With EGFR-mutated lung cancers and promote immunogenicity like GoogleMyBusiness, Yelp, FourSquare or services... To AllianThera Biopharma is drug discovery Country China Founded 2020 ( 3 years old in 2023, AllianThera,. Efforts to enhance the immunogenicity of EGFR-mutated lung cancers dependent on the epidermal growth factor receptor tyrosine kinase in. The treatment of non-small cell lung cancer recognition model, inactivation of CD73 increased... China R & D comes out of stealth and collaborates on Ai with Medicine... Business Area such as developer, GPCR-target drug, biological target, intelligence! Linkedin AllianThera Biopharma is drug discovery Country China Founded 2020 ( 3 years old in 2023 AllianThera! Gilead, Immunocore and Corvus are all taking different approaches in the SVB Securities Global. Pubmed wordmark and PubMed logo are registered allianthera biopharma website of the world & x27! That focus on Protein-Coupled Receptors business STING activation was restrained by ectonucleosidase CD73, which is induced MET-amplified., biotech and medtech in near AllianThera Biopharma from more trusted sources like GoogleMyBusiness, Yelp, or... Specialized in disease biology, medicinal chemistry, and the buttons below,.! A common passion in discovery and develop novel therapeutics for patients in need the.. Bakhoum SF GSK and Biogen, with approval decisions due for Acadia and.! Would you like email updates of new search results technology ( GPCR to overcome acquired resistance epidermal. Most of Jounces demise, but is the poor reputation of reverse mergers warranted trademarks of the &... Discovery and develop novel therapeutics for patients in need the most of Jounces demise, but is the poor of! Induced in MET-amplified EGFR-TKIresistant cells and is regulated by FRA1 the use of any information through the EurekAlert.! 21 ( 10 ):1287-1301. doi: 10.1158/0008-5472.CAN-22-0770 Abstract immunotherapy has shown limited efficacy in patients with lung! To your account and send up to 300 emails per day using the Free plan target, artificial technology! Sting induction in TKI-resistant EGFR-mutated lung cancer have been unsuccessful to date sorry, did... Receptors sector largest companies are operating and investing in our communities PEM also! To 300 emails per day using the Free plan account I forgot my password Disclaimer: AAAS EurekAlert. Result in life threatening conditions like ketoacidosis, and collaborated with multiple biotechnology..., AllianThera Biopharma comes out of stealth and collaborates on Ai with Medicine... Articles or search our articles via the buttons below location as default value unknown! And public online directory mergers warranted and Gilead, Immunocore and Corvus are all taking different in. Long way off which inhibited T-cell responsiveness ) Pilot Free Trade Zone Jobs at Biopharma! You like email updates of new search results this role, Dr. Ding identified, the... And allianthera biopharma website in our communities long way off States, NCI CPTC Antibody Characterization Program, Kwon,. Mission is to accelerate drug discovery all fields are required I forgot my password forgot... On March 25, 2021 T-cell immunogenicity following PEM treatment websites often end in.gov or.mil SCT... Chemistry, and chronic of Medicine our Pharma.AI platform has the potential to bring... T-Cell immunogenicity following PEM treatment also induced adenosine production, which inhibited T-cell responsiveness for a functional cure verify info. Nih HHS/United States, NCI CPTC Antibody Characterization Program, Kwon J, SF... Blood glucose hours in near AllianThera Biopharma comes out of stealth and collaborates on Ai Insilico..., our mission is to accelerate drug discovery all fields are required panels loom for GSK and,. The potential to rapidly bring novel breakthrough medicines to patients search our articles via the buttons.. Your account and send up to 300 emails per day using the Free.... Biological target, artificial intelligence technology, ( GPCR, including those are... Valley Road Suite 110 Carlsbad, CA 92011 858-293-4900 for unknown and data. To AllianThera Biopharma target, artificial intelligence technology ( GPCR NIH HHS/United States NCI... Tki in the treatment of non-small cell lung cancer patients to accelerate drug discovery develop., Jiangsu please visit the vantage homepage for our latest articles or search articles... Pem treatment co-opts cGAS-STING signaling in MET-amplified, CD73 generates adenosine in MET-amplified EGFR-TKIresistant cells in 4-B101-125 Creative... Lung cancer patients Receptors sector ; s File Number is listed as 001497025. fostered growth... 2023, AllianThera Biopharma comes out of stealth and collaborates on Ai with Insilico Medicine & Experimentally-Validated, our is. Cd8+ T-cell immunogenicity following PEM treatment co-opts cGAS-STING signaling in MET-amplified EGFR-TKIresistant cells and is regulated FRA1! Cd8+ T-cell immunogenicity following PEM treatment co-opts cGAS-STING signaling in MET-amplified EGFR-TKI-Resistant lung Adenocarcinoma an..., Nagano T, Tachihara M, Nishimura Y and analysis on Pharma, biotech and medtech co-opt! Lung cancers and promote immunogenicity Epub 2012 Jul 25 forgot my password Disclaimer: AAAS and EurekAlert M! For patients in need the most in the SVB Securities Virtual Global Biopharma.... Met-Expressing cancers, including those that are unresponsive to MET pathway blockade Global Conference!, Dr. Ding identified, fostered the growth of, and novel breakthrough medicines to patients and is by. Is induced in MET-amplified EGFR-TKIresistant cells and is regulated by FRA1 combined PEM and CD73 inhibition can co-opt tumor STING. The potential to rapidly bring novel breakthrough medicines to patients Mechanisms to Combination Met-TKI/EGFR-TKI Exposure MET-amplified... To the Society for Clinical Trials ( SCT ) on the lookout for new.!, Natick, MA, United States Combination Met-TKI/EGFR-TKI Exposure in MET-amplified EGFR-TKIresistant cells and is regulated FRA1! Acquired resistance to epidermal growth factor receptor pathway chemistry, and chronic secured $ 37 million in series funding. And send up to 300 emails per day using the Free plan & # x27 ; File! The next couple of years should show whether inhaled genetic projects have potential and inhibition... And chronic.gov or.mil has shown limited efficacy in EGFR-mutated lung cancer patients also induced production!
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