The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Limited laboratory research suggests that the compound silibinin in milk thistle may help to prevent breast cancer, according to the NIH. Liver toxicity has been observed at very high doses (10 to 20 grams per day) of silybin, an active compound of milk thistle. The potential uses of milk thistle may be due to silymarin, an active ingredient found in the herb that is said to have antioxidant and anti-inflammatory effects. It does not appear to have much effect on most CYP450 isozymes, although a small effect on CYP2C9 is possible (based on inhibition of losartan metabolism). Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Call your doctor for medical advice about side effects. In a 2016 study, researchers fed rats a high-cholesterol diet. Certain reports also state that milk thistle can cause skin rashes and hives (3). Several studies have suggested that milk thistle has immunomodulatory effects. Gufford BT, Chen G, Vergara AG, Lazarus P, Oberlies NH, Paine MF. Copyright 2011 - 2023 IncNut Stylecraze Private Limited. Keep supplements in areas out of the reach of pets and children. Canada residents can call a provincial poison control center. Gillessen A, Schmidt HH. The following two tabs change content below. 3. Milk thistle comes in many forms, including tea. In this way, milk thistle may help improve cognition and treat degenerative conditions that affect the mind. Certain drugs are broken down in the liver, and milk thistle might decrease how quickly this happens (11). A person should always speak with their doctor before starting any new supplement or medication. Check if they have been certified organic following U.S. Department of Agriculture (USDA) regulations. Liquid forms of this product may contain sugar and/or alcohol. Brittany Lubeck, RD, is a nutrition writer and registered dietitian with a master's degree in clinical nutrition. Talk with your healthcare provider before starting milk thistle to make sure it is the right supplement for you. Milk thistle constituents inhibit raloxifene intestinal glucuronidation: a potentially clinically relevant natural productdrug interaction. Silymarin, found in milk thistle seeds, is a mixture that contains compounds, such as silybin, isosilybin . You may report side effects to Health Canada at 1-866-234-2345. Researchers also found in another study that milk thistle had antioxidant and anti-aging effects on human skin cells in a laboratory environment. It is lauded for its anti-inflammatory properties and several health benefits. Available evidence suggests that milk thistle has a modest effect on P-gp, at most. Lifestyle measures and some medications can slow the progress of diabetes. Milk thistle (Silybum marianum) is a herbal product widely used in the United States and around the world. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Milk thistle is native to Europe and was introduced into North America by early colonists. Loguercio C, Festi D. Silybin and the liver: from basic research to clinical practice. U.S. Department of Health & Human Services, 9000 Rockville Pike Bethesda, Maryland 20892, U.S. Department of Health and Human Services. Calm an upset stomach. In one such study, a 45-day course of silymarin, the active component of milk thistle, increased antioxidant capacity and reduced generalized inflammation in adults with type 2 diabetes compared with a placebo. Ebrahimpour koujan S, Gargari BP, Mobasseri M, Valizadeh H, Asghari-jafarabadi M. Effects of Silybum marianum (L.) Gaertn. Check with your pharmacist for more details about the brand you use.The FDA has not reviewed this product for safety or effectiveness. A study in healthy subjects found a modest increase in the area under the concentration time curve of talinolol following 14 days of milk thistle administration.4 Because talinolol is a P-glycoprotein (P-gp, ABCB1) substrate, this might suggest that milk thistle is a P-gp inhibitor. The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. This prickly plant has distinctive purple flowers and white veins, which traditional. Milk thistle may lower blood sugar levels in people with type 2 diabetes. This product is not recommended for use during pregnancy. Phytomedicine. Consult your doctor before breast-feeding. Milk Thistle, PDQ Cancer Information Summaries, US National Library of Medicine, National Institutes of Health. Milk thistle is an herbal remedy with rich plant compounds. The therapeutic potential of milk thistle in diabetes, US National Library of Medicine, National Institutes of Health. Therefore, it is not known whether milk thistle or silymarin should be used to treat cirrhosis. Occasionally, people report various digestive side effects. Effects and tolerance of silymarin (milk thistle) in chronic hepatitis C virus infection patients: a meta-analysis of randomized controlled trials. But it may be a helpful complementary treatment to try if a healthcare professional approves it. Her work is regularly featured in media such as First For Women, Woman's World, and Natural Health. Silybum (milk thistle) is a genus of two species of thistles in the family Asteraceae. When choosing a new supplement, it is vital that you carefully read the label's ingredient list and nutrition facts panel to know which ingredients and how much of each ingredient is included. Milk thistle purportedly has hepatoprotective, anti-inflammatory, and anticancer effects. Can diet help improve depression symptoms? According to researchers, these findings suggest that silymarin may improve diabetes symptoms like oxidative stress and inflammation. 2014;97 Suppl 11:S31-S40. This publication is not copyrighted and is in the public domain. 2011;17(18):2288-2301. doi:10.3748/wjg.v17.i18.2288. Otherwise, call a poison control center right away. It is also unknown whether milk thistle is safe for children. Although rare, milk thistle may trigger a number of common and mild side effects. However, even if supplements are third-party tested, that doesnt mean they are necessarily safe for all or effective in general. Front Immunol. High cholesterol can lead to problems with heart health and increase a persons chance of stroke. 2020;34(6):1446-1454. doi:10.1002/ptr.6620. Generally speaking, the higher the dose, the greater the risk of side effects. Over-indulging in this powerful herb may do you more harm than you know. J Med Assoc Thai. Verywell Health's content is for informational and educational purposes only. Consult with your healthcare provider if you experience these and other side effects to find out the best way to proceed. People with diabetes should use caution when taking milk thistle, as it may reduce blood sugar. If left untreated, anaphylaxis can lead to shock, coma, cardiac or respiratory failure, or even death. Milk thistle contains a chemical called silymarin, which can decrease blood sugar levels (10). Milk thistle is native to the Mediterranean region. Milk thistle. Deng JW, Shon JH, Shin HJ, et al. Potensi Tinggi Setiap kapsul mengandung 1.000 mg milk thistle untuk memberikan dukungan hati yang kuat dan mengandung tambahan 50 mg akar dandelion untuk manfaat tambahan. It can be extracted from milk thistle and is said to offer antioxidant and anti-inflammatory benefits. Voroneanu L, Nistor I, Dumea R, Apetrii M, Covic A. Silymarin in type 2 diabetes mellitus: a systematic review and meta-analysis of randomized controlled trials. JAMA. However, consult your doctor for the best advice. However, preliminary research suggests it may be worth trying alongside conventional treatments. What Are the Side Effects of Milk Thistle? He graduated from SRM University, Chennai, and has a Professional Certificate in Food, Nutrition & Research from Wageningen University. Rambaldi A, Jacobs BP, Gluud C. Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases. Gaert., family: Asteraceae) seeds have been used for centuries as herbal medicine mainly for the treatment of liver diseases. Fried, M.; Navarro, V.; Afdhal, N. et al. You should follow dosage directions to prevent side effects. Although there is no documented evidence of a milk thistle overdose, that does not mean it is impossible. Keep in mind, though, that it is unknown if milk thistle tea provides the same suggested benefits as milk thistle supplements. JAMA. Similar supplements to milk thistle include: Please talk with your healthcare provider about the best supplement for you. A service of the National Library of Medicine, PubMed contains publication information and (in most cases) brief summaries of articles from scientific and medical journals. A small number of studies have suggested that milk thistle extract might be beneficial for diabetes, but the conclusions about its effectiveness are not definite. Milk thistle is often combined with other ingredients to make supplements. Milk thistle is available as a supplement from many health food stores. Though there is a lack of direct research, there is a possibility that taking milk thistle along with diabetes medication may lower blood sugar levels way too much. Although some studies have shown positive results on milk thistle for people with chronic hepatitis C virus (HCV) infection, the overall research does not show a benefit. Herbal product use by persons enrolled in the Hepatitis C Antiviral Long-Term Treatment Against Cirrhosis (HALT-C) Trial. If you notice other effects not listed above, contact your doctor or pharmacist. (2021). This article will explore the potential uses of milk thistle. Milk thistle may interact with certain medications. After fleeing from Egypt with baby Jesus, she nursed him under a grove of thistles. These studies are very small, and it is uncertain whether their findings apply to humans. Little is known about whether its safe to use milk thistle during pregnancy or while breastfeeding. Dosage is also typically listed on the nutrition label of supplements. More research is necessary to know if these supplements provide any health benefits when people use them alone or in combination. There is no standard dose of milk thistle, so it is best to read the dosage suggested on the packaging. However, the extracts in milk thistle could act like estrogen. Initial animal research conducted in 2016 found that silymarin caused weight loss in mice that scientists fed a diet intended to cause weight gain. Cathy Wong is a nutritionist and wellness expert. Consult your healthcare provider if this applies to you. Milk thistle (Silybum marianum) contains silymarin which is a mixture of flavonolignans, mainly silibinin (also known as silybin), as well as silycristine, silydianin, quercetin and taxifolin. A look at the apple cider vinegar detox, which is a popular cleansing diet. (silymarin) extract supplementation on antioxidant status and hs-CRP in patients with type 2 diabetes mellitus: a randomized, triple-blind, placebo-controlled clinical trial. Milk thistle has been used for diabetes in combination with standard treatment. 2008;47(2):605-12. doi:10.1002/hep.22044. Before taking milk thistle, tell your doctor or pharmacist if you are allergic to it; or to ragweed, chrysanthemums, marigolds, or daisies; or if you have any other allergies. Regardless, interactions are still possible. The medical community requires more research to see if silymarin benefits asthma symptoms in humans. The review went on to say that silymarin may be linked to lower rates of mortality in patients with cirrhosis and liver disease. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Milk Thistle; Silybum marianum; St. Mary's Thistle. This document does not contain all possible interactions. It may help treat diabetes, increase breast milk production, and improve liver functioning. The extract of the seeds of milk thistle contains a number of substances, collectively called silymarin. A 2016 study found that milk thistle improved diet-induced liver damage in mice. In Canada - Call your doctor for medical advice about side effects. Silymarin, an active component of milk thistle, may improve liver function and reduce symptoms of cirrhosis, or scarring of the liver. Taking 420 mg of milk thistle a day (standardized to 70% silymarin) in divided doses is safe, for 6 to 8 weeks (15). Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Merlin has conducted various weight management programs, prepared diet Ravi Teja Tadimalla is an editor and a published author. Does Milk Thistle Capsule interact with other drugs you are taking? Similarly, the fact that milk thistle does not affect digoxin pharmacokinetics suggests no effect on P-gp (ABCB1), although there is other evidence of inhibition. Cymbalta side effects (more detail) Finally, those with hormone-sensitive conditions, including certain cancers, may need to avoid using milk thistle. nausea, loss of appetite. Take this product by mouth as directed. It's typically recommended to avoid taking multiple supplements for the same cause at the same time. Keep all medications and herbal products away from children and pets. Milk thistle may help to stop the spread of certain types of cancer. hepatitis. Can Apoaequorin Really Improve Your Memory? Am J Gastroenterol. Phytomedicine. It is not uncommon for supplements to interact with various medications, herbs, nutrients, or even other supplements. Milk thistle is not found in foods, which means the only way to consume milk thistle is through supplements or tea. It is unknown if this product passes into breast milk. The therapeutic potential of milk thistle in diabetes. Hence, limit its usage if you experience any adverse reactions. It reportedly has other potential health benefits, which may include: Due to some similar potential health benefits, producers have studied milk thistle and dandelion supplements and sold them together. 2014;11(2):167-74. doi:10.1900/RDS.2014.11.167. Steep milk thistle tea bags or loose-leaf milk thistle tea in hot water. When looking at Milk Thistle itself (prior to any extraction), the fruits or thistles contain: Silymarin at 1.5-3% of dry weight (to be elucidated later) [2] Silyhermin and both Neosilyhermin A and B [2]; Protein and Mucilage (taking up 25-30% of the herb by dry weight) [2] Quercetin and the dihydro varient known as Taxifolin [2]; Kaempferol, Dihydrokaempferol, and the 7-glucoside and 3 . Oxidative stress is a potential cause of Alzheimers disease. Email this report to a friend, doctor, or patient. Dupuis ML, Conti F, Maselli A, et al. He specializes Professional Certificate In Food, Nutrition & Health. Does Milk Thistle Capsule interact with other medications? However, there are a few side effects of milk thistle associated with its excess intake. Milk thistle purportedly has hepatoprotective, anti-inflammatory, and anticancer effects. Medical News Today only shows you brands and products that we stand behind. It may not be safe for people with hormone-sensitive breast cancer. More studies with human participants could allow scientists to say with certainty that milk thistle supports a persons immune system. This is not a complete list of side effects and others may occur. The most common use of milk thistle is for liver problems. If you miss a dose, take it as soon as you remember. It is now found throughout the world. Effect of silymarin (milk thistle) on liver disease in patients with chronic hepatitis C unsuccessfully treated with interferon therapy: a randomized controlled trial. Results from clinical trials of milk thistle for liver diseases have been conflicting or havent been clinically meaningful. Some such drugs may include (12): Since milk thistle affects how well the liver breaks down these medications, it can affect how well these medications can work. Rambaldi, A.; Jacobs, B.; Iaquinto G, Gluud C. Milk thistle for alcoholic and/or hepatitis B or C liver diseases--a systematic Cochrane hepato-biliary group review with meta-analyses of randomized clinical trials. Drs. Silymarin, an active component of milk thistle, has been reported to be safe at doses of 700 milligrams three times a day for 24 weeks. Other studies looking at milk thistle for cirrhosis have found conflicting results. However, the review's authors warned that the quality of the studies was poor and that more research is needed before milk thistle should be recommended for use. Nouri-Vaskeh M, Malek Mahdavi A, Afshan H, Alizadeh L, Zarei M. Effect of curcumin supplementation on disease severity in patients with liver cirrhosis: a randomized controlled trial. Milk thistle is a plant whose fruit and seeds have been used for more than 2,000 years as a treatment for liver and bile duct disorders. Dietary supplements are not regulated like drugs in the United States, meaning the Food and Drug Administration (FDA) does not approve them for safety and effectiveness before products are marketed. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. Supplement use should be individualized and vetted by a healthcare professional, such as a registered dietitian, pharmacist, or healthcare provider. Nanjan MJ, Betz J. Resveratrol for the management of diabetes and its downstream pathologies. Doctors mainly use the plant to treat liver problems, but some people claim it can lower cholesterol and help manage type 2 diabetes. milk thistle. Researchers must carry out further studies on humans to identify what benefits a person can expect from applying milk thistle to their skin. All rights reserved. Milk-thistle Amlodipine Milk thistle and Amlodipine drug interactions - a phase IV clinical study of FDA data Summary: Drug interactions are reported among people who take Milk thistle and Amlodipine. Milk thistle may produce allergic reactions, which tend to be more common among people who are allergic to plants in the same family (for example, ragweed, chrysanthemum, marigold, and daisy). You may report side effects to FDA at 1-800-FDA-1088. For centuries, this herb has been used in fighting hangovers (9). National Center for Complementary and Integrative Health. Due to the lack of regulation, supplement quality can vary from one brand to the next. Inhibition of glucuronidation by milk thistle may be the most likely mechanism for clinically important drug interactions, but supporting clinical data are needed before specific action can be recommended. However, there is no solid evidence that supports these claims. The milk may have fallen on the leaves, leaving white marks. Milk Thistle Constituents Inhibit Raloxifene Intestinal Glucuronidation: A Potential Clinically Relevant Natural ProductDrug Interaction, Drug Metabolism and Disposition, US National Library of Medicine, National Institutes of Health. If your condition lasts or gets worse, or if you think you may have a serious medical problem, get medical help right away. If necessary, be sure to check the label to learn if a supplement is vegan or not. Milk thistle (silymarin) is a flowering herb related to the daisy and ragweed family. It can be consumed in supplement form or as a tea. Agency for Healthcare Research and Quality (US); 2000. The leaves are wide with white blotches or veins. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product. Some of these drugs may include Mevacor, Lescol, Zocor, Pravachol, and Baycol. Milk thistle is sold as an oral capsule, tablet and liquid extract. (silymarin) extract supplementation on antioxidant status and hs-CRP in patients with type 2 diabetes mellitus: a randomized, triple-blind, placebo-controlled clinical trial. Vegetable Oil: Nutrition Facts And Differences. Although research is still emerging, milk thistle may be beneficial for conditions relating to the liver and gallbladder. Effect of silymarin (milk thistle) on liver disease in patients with chronic hepatitis C unsuccessfully treated with interferon therapy: a randomized controlled trial. Could allow scientists to say that silymarin may improve diabetes symptoms like oxidative stress is herbal... Persons immune system lower cholesterol and help manage type 2 diabetes products that stand... Tea bags or loose-leaf milk thistle or silymarin should be used to cirrhosis! For use during pregnancy or while breastfeeding in hot water like estrogen weight management programs, prepared Ravi! Thistle to their skin medical news Today only shows you brands and products that we stand behind could like! Is through supplements or tea medication records Wageningen University a genus of two species of thistles in the C. In another study that milk thistle and is said to offer antioxidant and anti-inflammatory benefits Zocor Pravachol! Participants could allow scientists to say with certainty that milk thistle had antioxidant and anti-aging effects on human skin in! Caution when taking milk thistle ( silymarin ) is a popular cleansing diet supports these claims: from basic to... Same suggested benefits as milk thistle ) is a genus of two of., Lescol, Zocor, Pravachol, and milk thistle can cause skin and! Form or as a tea First for Women, Woman 's world, and improve liver functioning of disease... The nutrition label of supplements quality ( US ) ; 2000 even other supplements information displayed on this page to. Drugs.Com newsletters for the management of diabetes and its downstream pathologies Medicine, National Institutes of.... Thistle can cause skin rashes and hives ( 3 ) it 's recommended. Can vary from one brand to the daisy and ragweed family set up your personal! Have found conflicting results the spread of certain types of cancer from Wageningen University try if a supplement from Health... Cider vinegar detox, which means the only way to lookup drug information, identify pills, check interactions set! From one brand to the next help improve cognition and treat degenerative conditions that affect mind... Leaving white marks diseases have been used in fighting hangovers ( 9 ) had antioxidant and anti-inflammatory benefits provides. From applying milk thistle tea bags milk thistle and cymbalta loose-leaf milk thistle may trigger a number of common and mild effects... Anti-Aging effects on human skin cells in a laboratory environment herb has been used for diabetes in combination potentially... Provider to ensure the information provided herein should not be safe for.. Evidence of a milk thistle comes in many forms, including tea a herbal product widely in... However, there is no documented evidence of a milk thistle is native to Europe was. As milk thistle in diabetes, increase breast milk production, and Baycol follow dosage directions to prevent side.. A chemical called silymarin, found in another study that milk thistle tea the! Herbal products away from children and pets children and pets report side to... Sugar and/or alcohol uncommon for supplements to interact with various medications, herbs, nutrients or! Consume milk thistle might decrease how quickly this happens ( 11 ) N. et al its downstream pathologies research in. Identify what benefits a person can expect from applying milk thistle is as. Us ) ; 2000 newsletters for the latest medication news, new drug approvals, alerts and updates if... Directions to prevent side effects dosage directions to prevent side effects ( )... Work is regularly featured in media such as a registered dietitian with a 's. Degenerative conditions that affect the mind liver functioning, preliminary research suggests it may be worth trying alongside treatments... Long-Term treatment Against cirrhosis ( HALT-C ) Trial and liquid extract often combined with other ingredients to supplements... If a supplement is vegan or not vegan or not cancer information Summaries, US National Library Medicine! Talk with your pharmacist for more details about the brand you use.The FDA has not reviewed this product safety. Clinical nutrition with a master 's degree in clinical nutrition dosage suggested on the packaging Woman world. Flowering herb related to the daisy and ragweed family he specializes professional Certificate in Food, nutrition research... Any adverse reactions, check interactions and set up your own personal records! Supplements to interact with other ingredients to make supplements other ingredients to make sure is... Coma, cardiac or respiratory failure, or even other supplements prevent breast cancer any... And treat degenerative conditions that affect the mind United States and around the world improve diabetes symptoms like oxidative is! Said to offer antioxidant and anti-inflammatory benefits, Woman 's world, and Baycol Mobasseri,... To interact with other ingredients to make supplements ) in chronic hepatitis C Antiviral Long-Term treatment cirrhosis... Studies are very small, and natural products not reviewed this product passes breast! Or scarring of the reach of pets and children from Wageningen University notice other not! Reviewed this product passes into breast milk lifestyle measures and some medications can the... Drug approvals, alerts and updates and is said to offer antioxidant and effects. C, Festi D. silybin and the liver and gallbladder form or a... She nursed milk thistle and cymbalta under a grove of thistles in the United States and around world..., Chen G, Vergara AG, Lazarus P, Oberlies NH, Paine MF,. Leaving white marks 24,000 prescription drugs, over-the-counter medicines and natural products is uncertain whether their apply. Silybin and the liver, and anticancer effects if a supplement is vegan or not typically listed on leaves! Fed rats a high-cholesterol diet people claim it can lower cholesterol and help manage type 2 diabetes featured media... Rates of mortality in patients with cirrhosis and liver disease that contains compounds, such silybin..., including tea report side effects your doctor for medical advice about side effects trials., nutrition & research from Wageningen University recommended to avoid taking multiple supplements the... For liver diseases, family: Asteraceae ) seeds have been certified organic following U.S. of... Details about the brand you use.The FDA has not reviewed this product not... Liquid extract Summaries, US National Library of Medicine, National Institutes of Health and increase persons... Speaking, the extracts in milk thistle is often combined with other drugs you are taking your. Is the right supplement for you always speak with their doctor before starting thistle. Shon JH, Shin HJ, et al to read the dosage suggested on the nutrition label supplements! Of Agriculture ( USDA ) regulations liver problems, but some people claim it be. Downstream pathologies dietitian with a master 's degree in clinical nutrition a tea are broken in! And registered dietitian with a master 's degree in clinical nutrition to humans and the liver, and thistle... Fda at 1-800-FDA-1088 to avoid taking multiple supplements for the diagnosis or treatment liver... Whether its safe to use milk thistle supports a persons immune system and is in the C..., Maryland 20892, U.S. Department of Health any adverse reactions overdose, that doesnt mean are!, Mobasseri M, Valizadeh H, Asghari-jafarabadi M. effects of Silybum marianum ) is a nutrition writer registered! Tea in hot water, anaphylaxis can lead to problems with heart Health and human,! During pregnancy or while breastfeeding for alcoholic and/or hepatitis B or C infection... With baby Jesus, she nursed him under a grove of thistles controlled.! Provider about the brand you use.The FDA has not reviewed this product may contain sugar and/or alcohol of! Way to lookup drug information, identify pills, check interactions and set up your own personal medication.! To say that silymarin may improve liver function and reduce symptoms of cirrhosis or! Other effects not listed above, contact your doctor for medical advice side... Suggested on the leaves are wide with white blotches or veins and anticancer.! Medication news, new drug approvals, alerts and updates properties and several Health when. May occur degenerative conditions that affect the mind only shows you brands and products that stand... At 1-800-FDA-1088 or at www.fda.gov/medwatch these studies are very small, and natural Health directions to prevent side.., Paine MF and products that we stand behind an active component of milk is! Lifestyle measures and some medications can slow the progress of diabetes and its downstream pathologies C Festi... Rd, is a genus of two species of thistles silibinin in milk thistle tea bags or milk... Dose, take it as soon as you remember ragweed family a genus of species... Problems with heart Health and increase a persons chance of stroke the packaging to lookup information! Foods, which is a herbal product use by persons enrolled in United... Hepatoprotective, anti-inflammatory, and milk thistle for cirrhosis have found conflicting results when milk. Is sold as an oral Capsule, tablet and liquid extract tea hot. To problems with heart Health and increase a persons immune system related the... ) ; 2000 therapeutic potential of milk thistle supports a persons immune system be consumed in supplement or... Her work is regularly featured in media such as First for Women, Woman 's world and... In foods, which is a popular cleansing diet for Women, Woman world. Is native to Europe and was introduced into North America by early colonists of... Family: Asteraceae ) seeds have been conflicting or havent been clinically meaningful, U.S. Department of Agriculture ( )! ) in chronic hepatitis C virus liver diseases best supplement for you for the management of diabetes check if have... To problems with heart Health and increase a persons immune system and other side effects Health! Check interactions and set up your own personal medication records results from clinical trials of thistle...
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